However, this also brought the Vault to the attention of the Fiends. For a couple of weeks, it went well and the inhabitants made a good living. The original Vault 3 inhabitants opened their doors and began to trade with people outside of the Vault. All was going well in the Vault until a water leak occurred sometime in the 23rd century, forcing the residents to open the Vault to find help.
Nestled within the South Vegas ruins, Vault 3 was one of the seventeen control Vaults, resulting in it not having an experiment.
Vault 3 is one of four Vaults in the Mojave that contains living human inhabitants, the others being Vault 19, Vault 21, and Vault 34.